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Immunometabolism and Inflammation

Dear Colleagues,

The first event in the inflammatory response consists in the recruitment of circulating monocytes and other myeloid cells to specific locations, such as bacterial entry sites, ischemic tissues, intratumoral areas, or atherosclerosis plaques. These pathological sites are normally associated with inadequate or abnormal vascularization, which subsequently compromises appropriate oxygen supply and metabolite exchange. It is now clear that metabolites, metabolic competition and nutrient restriction contribute to the immune response, determining disease outcome. This special issue of Immunometabolism aims to provide a series of articles covering all the aspects to point out how metabolic reprogramming and metabolic cross-talk control innate immunity and inflammatory cell phenotypes during acute and chronic inflammation such as cancer, ischemia, atherosclerosis and infections. We are welcoming submissions of both original research articles and review articles related to this topic.

Professor Massimiliano Mazzone

Guest Editor


Metabolic Reprogramming

Metabolic competition

Metabolic cross-talk

Innate Immunity



Myeloid-derived suppressor cells

Myeloid cells


Acidity and pH






Phenotypic Polarization

Submission Deadline: 15 June 2019

Online Submission

Manuscripts should be submitted online through Hapres Online Submission System. Please visit Guide for Authors before submitting a manuscript. Authors are encouraged to submit a paper as soon as it is ready and don’t need to wait until the deadline. Submissions will be sent to peer-review in order of arrival. Accepted papers will be published continuously in Immunometabolism and then gathered together on the special issue webpage. We welcome Research articles, Review papers and Short Communications. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

See Papers Published in This Special Issue (6 papers)


Virtual Special Issue (VSI) is a collection of papers centered around a specific topic, led by an expert (Guest Editor) in the field. Virtual Special Issues are an important component of our journal and cover current hot topics within the scope of the journal.

All papers belonging to a Virtual Special Issue will be gathered together on a single webpage. They are published in the regular issues of the journal as soon as publishable, and labeled as belonging to the Virtual Special Issue. A link from each paper will take you to the Virtual Special Issue website.

Submissions to Virtual Special Issues will undergo the same rigorous peer-review process as regular papers submitted to the journal.

Guest Editor

  • Professor Massimiliano Mazzone

    VIB, KU Leuven

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